RWD often varies in format and includes gaps or missing data, inconsistencies, and biases, making careful management and attention to quality imperative. Optimal quality review is essential to ensure data integrity and uphold credibility.

Use Cases for Hospital-Derived RWE in Clinical Research:

• Reducing the time, cost, and burden of clinical trials
• Addressing comparative effectiveness
• Assessing health care utilization
• Understanding real-world outcomes
• Refining precision medicine
• Responding to urgent need